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[P84]: The onecut transcription factors HNF‐6 and OC‐2 control the development of the spinal motor neurons
Author(s) -
Clotman F.
Publication year - 2006
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/j.ijdevneu.2006.09.147
Subject(s) - neuroscience , chemistry , biology
Early developing neuronal cells are known to contain an elevated intracellular chloride concentration. The passive conductance has an important chloride component besides the potassium ion movement. The mechanisms establishing the high intracellular chloride content, however, are far from clear. Our data suggest that voltage dependent chloride channels may function in neural stem and progenitor cells besides the passive move of chloride through gap junction channels.