[P29]: A novel test protocol for assessing children with autistic spectrum disorders | Zendy

Rivera C. | Zendy; Thiele S. | Zendy; Khattak S. | Zendy; Milgram N.W. | Zendy

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[P29]: A novel test protocol for assessing children with autistic spectrum disorders

Author(s) -

Rivera C.,

Thiele S.,

Khattak S.,

Milgram N.W.

Publication year - 2006

Publication title -

international journal of developmental neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.761

H-Index - 88

eISSN - 1873-474X

pISSN - 0736-5748

DOI - 10.1016/j.ijdevneu.2006.09.093

Subject(s) - milgram experiment , test (biology) , library science , citation , media studies , psychology , sociology , computer science , social psychology , paleontology , biology , obedience

an independent study by an additional group. We have therefore begun to characterize the function of AGC1 in cell and animal models. We have developed mice with a targeted disruption of AGC1. Remarkably, the AGC1-deficient animals have profound decrease in the levels of structural myelin proteins. This appears to be due to a significant decrease in the levels of N-acetylaspartate (NAA), which is important in myelin lipid synthesis. Further characterization of this model will shed light on the role of AGC1 in brain function and may shed light on a molecular and cellular pathology that may contribute to autism susceptibility.

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