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[P14]: Transplanted Schwann cells engineered to over‐express polysialic acid promote regenerative axonal outgrowth of purkinje cells in L1/GAP‐43 double transgenic mice
Author(s) -
Zhang Y.,
Zhang X.,
Wu D.,
Yeh J.,
Richardson P.,
Bo X.
Publication year - 2006
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/j.ijdevneu.2006.09.078
Subject(s) - queen (butterfly) , theology , art history , biology , art , philosophy , botany , hymenoptera
Vh = 29.76 ± 1.16, n = 10, P < 0.01, without changing the slope factor), and the steady-state inactivation curve of INa, IA toward negative potential (INa Vh = −67.38 ± 5.49 mV, versus AlCl3 Vh = −71.35 ± 4.36, n = 10, P < 0.05; IA control Vh = −52.87 ± 1.92 mV, versus AlCl3 Vh = −60.50 ± 1.36 mV, n = 10, P < 0.05, without changing the slope factor). These results imply that AlCl3 may damage sodium and potassium channels of the hippocampal CA1 neurons from rats and this may be related to the mechanism of the damage to the central nervous system by aluminum.