Open AccessCoronary thrombus in 34-year-old female patient with 4G/4G polymorphism in the PAI-1 gene
Author(s) -
Sinan Varol,
Muhsin Kalyoncuoğlu,
Burak Ayça,
İrfan Şahin,
Gökmen Kum,
Sevgi Özcan,
Ertuğrul Okuyan
Publication year - 2016
Publication title -
international journal of the cardiovascular academy
Language(s) - English
Resource type - Journals
eISSN - 2618-6012
pISSN - 2405-8181
DOI - 10.1016/j.ijcac.2016.03.002
Subject(s) - medicine , thrombus , myocardial infarction , cardiology , thrombosis , coronary thrombosis , plasminogen activator inhibitor 1 , tissue plasminogen activator , infarction , polymorphism (computer science) , plasminogen activator , stroke (engine) , gene , genotype , genetics , biology , mechanical engineering , engineering
Genetic factors and hypofibrinolytic state may contribute to the likelihood of developing in myocardial infarction (MI) in young women rather than traditional risk factors. High plasminogen-activator inhibitor-1 (PAI-1) level and PAI-1 gene polymorphism have been shown to be associated with thrombotic events such as myocardial infarction, deep venous thrombosis, and stroke. We determined 4G/4G polymorphism in a 34-year-old female patient with subacute anterior myocardial infarction and coronary thrombus in left anterior descending artery on coronary angiogram