Open AccessPrimary percutaneous coronary intervention for coronary thrombosis during cisplatin, etoposide and bleomycin combination therapy under thromboprophylaxis with nadroparin
Author(s) -
Mehmet Yaman,
Senar Ebinç,
Osman Beton,
Türkan Mete
Publication year - 2015
Publication title -
international journal of the cardiovascular academy
Language(s) - English
Resource type - Journals
eISSN - 2405-819X
pISSN - 2405-8181
DOI - 10.1016/j.ijcac.2015.07.009
Subject(s) - medicine , percutaneous coronary intervention , thrombosis , cisplatin , coronary thrombosis , bleomycin , cardiology , chemotherapy , myocardial infarction
Testicular cancer is the most common solid tumor among young men. Regimens containing cisplatin and bleomycin in combination with etoposide are used for treatment of non-seminomatous germ cell testicular tumors. Cancer patients are at increased risk of thrombosis. Epidemiological studies have identified chemotherapy as an additional risk factor for a hypercoagulability state and thrombosis. The risk is more pronounced with cisplatin-containing chemotherapy. Thromboprophylaxis with LMWH during chemotherapy has demonstrated to give substantial risk reduction of thromboembolic events. We present a case of acute myocardial infraction during combined chemotherapy with bleomycin, etoposide and cisplatin for testicular cancer under thromboprophylaxis with nadroparin. Emergency coronary angiography revealed total occlusion of the right coronary artery by a thrombus which was successfully removed by aspiration