Survival following relapse after allogeneic hematopoietic cell transplantation for acute leukemia and myelodysplastic syndromes in the contemporary era
Author(s) -
Sanghee Hong,
Lisa Rybicki,
Donna Corrigan,
Betty K. Hamilton,
Ronald Sobecks,
Matt Kalaycio,
Aaron T. Gerds,
Rob M. Dean,
Brian T. Hill,
Brad Pohlman,
Deepa Jagadeesh,
Faiz Anwer,
Navneet S. Majhail
Publication year - 2020
Publication title -
hematology/oncology and stem cell therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 22
eISSN - 1658-3876
pISSN - 2589-0646
DOI - 10.1016/j.hemonc.2020.11.006
Subject(s) - medicine , hazard ratio , transplantation , myelodysplastic syndromes , myeloid leukemia , hematopoietic stem cell transplantation , oncology , leukemia , surgery , confidence interval , bone marrow
Relapse is the most common cause of treatment failure after allogeneic hematopoietic cell transplantation (alloHCT). No standard of care exists, and a wide range of treatments are used for post-alloHCT relapse. In the recent era, several novel therapies including targeted agents are available for acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), and myelodysplastic syndrome (MDS).
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