Spectrum of myelodysplastic syndrome in patients evaluated for cytopenia(s). A Report from a Reference Centre in Saudi Arabia
Author(s) -
Nour AlMozain,
Ayman Mashi,
Qasem Alneami,
Amal Al-Omran,
Nasir Bakshi,
Tarek Owaidah,
Salem Khalil,
Haitham Khogeer,
Shahrukh K. Hashmi,
Suleimman AlSweedan,
Thomas Morris,
Randa Alnounou
Publication year - 2020
Publication title -
hematology/oncology and stem cell therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 22
eISSN - 1658-3876
pISSN - 2589-0646
DOI - 10.1016/j.hemonc.2020.11.001
Subject(s) - cytopenia , myelodysplastic syndromes , medicine , dysplasia , trisomy 8 , bone marrow , international prognostic scoring system , hematology , pathology , oncology , cytogenetics , chromosome , biology , genetics , gene
Myelodysplastic syndrome (MDS) is a clonal disorder of hematopoietic stem cells, characterized by ineffective hematopoiesis, peripheral cytopenias along with hypercellularity of the bone marrow, and marked dysplastic features. Establishing MDS diagnosis is difficult due to nonspecific clinical presentation and imprecise morphological criteria. In anticipation to improve the diagnostic approach in this field, we aimed to characterize the clinical and morphological features of patients presented with cytopenias with a special focus on MDS.
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