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Frequency of MYD88 L256P mutation and its correlation with clinico-hematological profile in mature B-cell neoplasm
Author(s) -
Raja Shekhar,
Shano Naseem,
Jogeshwar Binota,
Neelam Varma,
Pankaj Malhotra
Publication year - 2020
Publication title -
hematology/oncology and stem cell therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 22
eISSN - 1658-3876
pISSN - 2589-0646
DOI - 10.1016/j.hemonc.2020.10.003
Subject(s) - neoplasm , mutation , correlation , myeloproliferative neoplasm , biology , medicine , cancer research , genetics , bone marrow , mathematics , gene , geometry , myelofibrosis
B-cell neoplasms are clonal tumors of B cells at various stages of maturation, including diffuse large B-cell lymphoma (DLBCL), chronic lymphocytic lymphoma (CLL), Burkitt lymphoma (BL), lymphoplasmacytic lymphoma (LPL)/Waldenström's macroglobulinemia (WM), splenic marginal zone lymphoma (SMZL), nodal marginal zone lymphoma (NMZL), mantle cell lymphoma (MCL), follicular lymphoma (FL), and hairy cell leukemia (HCL). In this study, we analyzed the frequency of MYD88 L265P mutation and its correlation with clinico-hematological profile in mature B-cell neoplasms.

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