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Twice-daily intravenous bolus tacrolimus infusion: A safe and effective regimen for graft-versus-host disease prophylaxis
Author(s) -
Hamza Hashmi,
Shruti Bhandari,
Rohit Kumar,
Prashant Tripathi,
Jill Blancett Rhodes,
Lindsay Figg,
Timothy Baize,
Maxwell M. Krem,
Mohamed Hegazi,
Robert Emmons
Publication year - 2020
Publication title -
hematology/oncology and stem cell therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 22
eISSN - 1658-3876
pISSN - 2589-0646
DOI - 10.1016/j.hemonc.2020.03.002
Subject(s) - tacrolimus , medicine , toxicity , dosing , bolus (digestion) , graft versus host disease , clinical endpoint , regimen , gastroenterology , transplantation , surgery , anesthesia , clinical trial
Among patients undergoing allogeneic hematopoietic cell transplant, continuous intravenous (IV) tacrolimus infusion is frequently used for graft-versus-host disease (GvHD) prophylaxis. Twice-daily intermittent IV tacrolimus dosing may confer safety and convenience benefits.

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