Comparative effectiveness of busulfan/cyclophosphamide versus busulfan/fludarabine myeloablative conditioning for allogeneic hematopoietic cell transplantation in acute myeloid leukemia and myelodysplastic syndrome
Author(s) -
Sagar S. Patel,
Lisa Rybicki,
Brad Pohlman,
Brian J. Bolwell,
Aaron T. Gerds,
Betty K. Hamilton,
Rabi Hanna,
Matt Kalaycio,
Navneet S. Majhail,
Ronald Sobecks
Publication year - 2019
Publication title -
hematology/oncology and stem cell therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 22
eISSN - 1658-3876
pISSN - 2589-0646
DOI - 10.1016/j.hemonc.2019.09.002
Subject(s) - busulfan , fludarabine , medicine , myeloid leukemia , myelodysplastic syndromes , cyclophosphamide , hematopoietic cell , hematopoietic stem cell transplantation , transplantation , oncology , haematopoiesis , chemotherapy , stem cell , biology , bone marrow , genetics
Busulfan/cyclophosphamide (Bu/Cy) and busulfan/fludarabine (Bu/Flu) are both standard myeloablative conditioning (MAC) regimens for allogeneic hematopoietic cell transplantation (alloHCT). We compared the effectiveness of these regimens with a focus on quality of life (QOL).
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