Philadelphia chromosome-positive lymphoblastic lymphoma—Is it rare or underdiagnosed? | Zendy

Ahmad Alshomar | Zendy; Riad El Fakih | Zendy

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Philadelphia chromosome-positive lymphoblastic lymphoma—Is it rare or underdiagnosed?

Author(s) -

Ahmad Alshomar,

Riad El Fakih

Publication year - 2018

Publication title -

hematology/oncology and stem cell therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.666

H-Index - 22

eISSN - 1658-3876

pISSN - 2589-0646

DOI - 10.1016/j.hemonc.2018.05.007

Subject(s) - lymphoblastic lymphoma , medicine , lymphoma , chromosome , oncology , cancer research , pediatrics , genetics , biology , immunology , t cell , gene , immune system

Lymphoblastic lymphomas (LBLs) are neoplasms of precursor B and T cells; they are considered in the same spectrum as precursor B and T cell acute lymphoblastic leukemia (ALL). The World Health Organization classification classifies both LBL and ALL as one disease entity. While chromosome abnormalities are well defined with all of their therapeutic and prognostic implications in ALL, these are not well studied in LBL. Here, we describe a case of Philadelphia chromosome-positive LBL and review the available literature regarding this entity.

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