Myasthenia gravis after allogeneic bone marrow transplantation: A case report and literature review
Author(s) -
Yutaka Tsutsumi,
Takashi Kamiishi,
Ryo Kikuchi,
Shinichi Ito,
Satomi Matsuoka,
Takanori Teshima
Publication year - 2017
Publication title -
hematology/oncology and stem cell therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 22
eISSN - 1658-3876
pISSN - 2589-0646
DOI - 10.1016/j.hemonc.2017.04.001
Subject(s) - medicine , myasthenia gravis , hematopoietic stem cell transplantation , myeloid leukemia , transplantation , disease , weakness , surgery , graft versus host disease , myeloid
A 52-year-old man with acute myeloid leukemia underwent allogeneic hematopoietic stem cell transplantation and developed extensive chronic graft-versus-host disease and myasthenia gravis (MG), which became involved with oculobulbar and proximal upper and lower limb weakness in 677days. In the literature, we identified 24 cases where MG developed after allo-SCT. Graft-versus-host disease development and male recipients of female donors might be prone to the development of posttransplant MG (odds ratio, 3.75).
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