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Experiencia del Instituto Regional de Tratamiento del Cáncer en el manejo del cáncer cervicouterino con radioterapia
Author(s) -
Ciria Vázquez Macías,
Mónica Miroslava García Silva,
Emilio Torres Medina,
José Francisco Figueroa Sandoval
Publication year - 2016
Publication title -
gaceta mexicana de oncología
Language(s) - Spanish
Resource type - Journals
SCImago Journal Rank - 0.106
H-Index - 4
eISSN - 2565-005X
pISSN - 1665-9201
DOI - 10.1016/j.gamo.2016.07.009
Subject(s) - medicine , gynecology , radiation therapy , surgery
ResumenIntroducciónEl cáncer del cuello del útero es un problema importante de salud pública en nuestro país. El tratamiento del carcinoma cervicouterino (Ca. Cu.) depende de la etapa clínica. Las modalidades terapéuticas han sido cirugía, la radioterapia y el tratamiento combinado con radioterapia más quimioterapia.ObjetivoInformar la experiencia del Instituto Regional del Tratamiento del Cáncer (IRTC) en pacientes con cáncer del cuello del útero, tratadas con radioterapia externa más braquiterapia con Iridio 192.MétodoEs un estudio descriptivo, retrospectivo, de 32 pacientes con cáncer del cuello de la matriz tratadas con radioterapia externa con acelerador lineal, una dosis de 5,000cGy (técnica isocéntrica) más braquiterapia de alta tasa, una dosis de 2,100cGy en 3 sesiones; sin embargo, las pacientes con la etapa iA2 solo recibieron braquiterapia y tuvieron un seguimiento mínimo 2 años.ResultadosEtapa iA2, 2 pacientes, etapa iB1 y iB2, 7 pacientes, etapa iiA, un paciente, etapa iiB, 11 pacientes, etapa iiiB, 8 pacientes, etapa ivA, un paciente, NCTFU, 2 pacientes, solamente 3 pacientes –2 en etapa iiB y una en etapa iiiB– recibieron quimioterapia concomitante. Morbilidad inicial: cistitis grado ii 3 pacientes, proctitis grado ii 3 pacientes; en lo que se refiere a la morbilidad tardía: proctitis grado ii 3 pacientes, cistitis grado i 3 pacientes, sinequia parcial 5 pacientes, sinequia completa 4 pacientes. La sobrevida sin AT, 23 pacientes, realizando el desglose: etapa iA2, iB1-iB2, iiA todas vivas, de la etapa iiB solo 7 pacientes, de la iiiB 4 pacientes, el ivA una viva, al igual que una de las NCTFU. En lo que se refiere a los MCAT, son 9 pacientes, distribuidos de la siguiente manera: 4 pacientes etapa iiB, 4 pacientes etapa iiiB y uno NCTFU.ConclusiónEl control locorregional y la sobrevida son similares a lo informado en la literatura y con menor morbilidad.AbstractBackgroundCervical uterine cancer (CUC) is an important public health problem in our country. The treatment of this cancer depends on the clinical stage. The therapeutic modalities used may be surgery, radiotherapy, and a combination of radiotherapy plus chemotherapy.ObjectiveTo describe the experience of the Regional Institute of Cancer Treatment (RICT) in patients with cervical cancer treated with external radiotherapy plus brachytherapy with iridium 192.MethodA descriptive, retrospective study was conducted on 32 patients with cervical uterine cancer treated by external radiotherapy with linear accelerator, a 5000 dose of cGy (isocentric technique) plus 2100 cGy with high dose rate (HDR) brachytherapy in 3 sessions. Patients with clinical stage IA2 were treated only with brachytherapy, with a minimum follow-up of 2 years.ResultsThere were 2 patients in stage IA2, 7 in stage IB1-IB2, 1 patient in IIA, 11 patients in IIB, 8 in stage IIIB, 1 patient in stage IVA 1, and 2 patients unclassified. Only 3 patients (2 in stage IIB, and 1 in stage IIIB) were treated with concomitant chemotherapy. Immediate morbidity was grade II cystitis in 3 patients and grade III proctitis in 3 patients. The delayed morbidity included grade II proctitis in 3 patients, grade I cystitis in 3 patients, partial synechiae in 5 patients, and complete synechiae in 4 patients. Twenty-three patients survived with no tumour activity, which included, brachytherapy only in 2 in stage IA, 7 in IB1-IB2, 1 in IIA, 7 in stage IIB, 4 in stage IIIB, 1 in stage IVA, and 1 in unclassified. Of the 9 patients that died, 4 were in stage IIB, 4 in stage IIIB, and 1 unclassified.ConclusionLocoregional control and survival are similar to those reported in the literature, but with less morbidity

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