Open AccessExtraction and isolation of new compounds from traditional herbal medicine; Clerodendrum phlomidis Linn.
Author(s) -
Mohammed Jameel,
Abuzer Ali,
Mohammed Ali
Publication year - 2017
Publication title -
future journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2314-7253
pISSN - 2314-7245
DOI - 10.1016/j.fjps.2017.04.003
Subject(s) - traditional medicine , isolation (microbiology) , extraction (chemistry) , folk medicine , medicine , biology , chemistry , chromatography , microbiology and biotechnology
Clerodendrum phlomidis L., (Lamiaceae), is a shrub, generally found in south-east Asia. This genus has great ethno-medicinal importance in various indigenous systems of medicine like Indian, Chinese, Thai, Korean, Siddha, Unani and Japanese for the treatment of numerous diseases like syphilis, typhoid, cancer, jaundice, hypertension, constipation, gonorrhea, piles, urinary diseases, nervous disorders, inflammation and measles. Isolation of three new compounds from methanolic extracts of roots of plant namely 3′-stigmast-5-enyl-4′-octadecanyl protocatechuic acid (2), n-tetratriacont-24-enoic acid (3), n-tetradecanyl- glucopyranosyl–(2′→1″) glucopyranoside (5) along with known β-sitosteryl n-octadec-9′,12′-dienoate (1), n-octadec-9-enoyl- β-D-arabinopyranoside (4) and α-D-glucopyranosyl-(6→1′)-α-D-glucopyranosyl-(6′→1″)-α-D-glucopyranoside (6) have been done on the basis of spectral data analysis and chemical means