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Insights into the behavioral difference of water in the presence of GM1
Author(s) -
Basu Ipsita,
Manna Moutusi,
Mukhopadhyay Chaitali
Publication year - 2015
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2015.11.014
Subject(s) - bound water , lipid bilayer , chemical physics , biomolecule , surface (topology) , surface water , molecule , biophysics , chemistry , molecular dynamics , materials science , nanotechnology , computational chemistry , membrane , environmental science , mathematics , biochemistry , biology , organic chemistry , environmental engineering , geometry
Studies on the structure and dynamics of interfacial water, emphasizing on the properties of water near the surface of biomolecules, are well reported, but there is a lack of evidence on the behavior of water near a comparatively rough surface containing molecules with a bulky head group like GM1. In this report we comparatively analyze the structure and dynamics of water as a function of distance from the lipid head group in GM1 containing lipid bilayers, with the lipid bilayers where GM1 is not present. This approach effectively demonstrates the behavioral difference and hence delayed convergence from bound water to bulk water in the presence of GM1 compared to a relatively smooth surface.