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Roles of LIM kinases in central nervous system function and dysfunction
Author(s) -
Cuberos H.,
Vallée B.,
Vourc'h P.,
Tastet J.,
Andres C.R.,
Bénédetti H.
Publication year - 2015
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2015.10.032
Subject(s) - neuroscience , function (biology) , kinase , central nervous system , nervous system , biology , microbiology and biotechnology
We finally present the existence of a cofilin‐independent pathway also involved in neuronal function. A better understanding of the differences between both LIMKs and of the precise molecular mechanisms involved in their mode of action and regulation is now required to improve our understanding of the physiopathology of the neuronal diseases associated with LIMKs.