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Communication between circadian clusters: The key to a plastic network
Author(s) -
Beckwith Esteban J.,
Ceriani M. Fernanda
Publication year - 2015
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2015.08.017
Subject(s) - signalling , flexibility (engineering) , neuroscience , circadian clock , key (lock) , circadian rhythm , hierarchy , neuropeptide , biology , computer science , chemistry , microbiology and biotechnology , receptor , ecology , biochemistry , statistics , mathematics , economics , market economy
It is increasingly clear that the fly clock employs multiple signalling cues, such as neuropeptides, fast neurotransmitters, and other signalling molecules, in the dynamic interplay between neuronal clusters. These neuronal groups seem to interact in a plastic fashion, e.g., rearranging their hierarchy in response to changing environmental conditions. A picture is emerging supporting that these dynamic mechanisms are in place to provide an optimal balance between flexibility and an extraordinary accuracy.