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Telomere length regulation in budding yeasts
Author(s) -
Malyavko Alexander N.,
Parfenova Yuliya Y.,
Zvereva Maria I.,
Dontsova Olga A.
Publication year - 2014
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2014.05.049
Subject(s) - telomere , nucleoprotein , biology , budding yeast , genome , saccharomyces cerevisiae , budding , telomere binding protein , microbiology and biotechnology , computational biology , genetics , rna , dna , yeast , gene , dna binding protein , transcription factor
Telomeres are the nucleoprotein caps of chromosomes. Their length must be tightly regulated in order to maintain the stability of the genome. This is achieved by the intricate network of interactions between different proteins and protein–RNA complexes. Different organisms use various mechanisms for telomere length homeostasis. However, details of these mechanisms are not yet completely understood. In this review we have summarized our latest achievements in the understanding of telomere length regulation in budding yeasts.