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Phosphatidylglycerol biosynthesis is required for the development of embryos and normal membrane structures of chloroplasts and mitochondria in Arabidopsis
Author(s) -
Tanoue Ryo,
Kobayashi Megumi,
Katayama Kenta,
Nagata Noriko,
Wada Hajime
Publication year - 2014
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2014.03.010
Subject(s) - chloroplast , arabidopsis , thylakoid , plastid , biosynthesis , mutant , phosphatidylglycerol , mitochondrion , atp synthase , biochemistry , embryo , microbiology and biotechnology , biology , arabidopsis thaliana , membrane , chemistry , gene , phospholipid , phosphatidylcholine
Phosphatidylglycerophosphate (PGP) synthase, encoded by PGP1 and PGP2 in Arabidopsis , catalyzes a committed step in the biosynthesis of phosphatidylglycerol (PG). In this study, we isolated a pgp1pgp2 double mutant of Arabidopsis to study the function of PG. In this mutant, embryo development was delayed and the majority of seeds did not germinate. Thylakoid membranes did not develop in plastids, mitochondrial membrane structures were abnormal in the mutant embryos, and radiolabeling of phospholipids showed that radioactivity was not significantly incorporated into PG. These results demonstrated that PG biosynthesis is essential for the development of embryos and normal membrane structures of chloroplasts and mitochondria.