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Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors
Author(s) -
Zanotti Giuseppe,
Cendron Laura,
Folli Claudia,
Florio Paola,
Imbimbo Bruno Pietro,
Berni Rodolfo
Publication year - 2013
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2013.06.016
Subject(s) - fibrillogenesis , transthyretin , chemistry , native state , biophysics , conformational change , fibril , in vitro , biochemistry , stereochemistry , biology , endocrinology
TTR and TTR bind by x‐ray crystallography ( View interaction )