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Tumor suppressor protein VHL inhibits Hedgehog–Gli activation through suppression of Gli1 nuclear localization
Author(s) -
Cho Hyun Kook,
Kim So Young,
Kim Kook Hwan,
Kim Hyeong Hoe,
Cheong JaeHun
Publication year - 2013
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2013.01.050
Subject(s) - gli1 , hedgehog signaling pathway , hedgehog , transactivation , suppressor , transcription factor , cancer research , gli2 , biology , sonic hedgehog , smoothened , indian hedgehog , nuclear protein , microbiology and biotechnology , signal transduction , gene , genetics
VHLphysically interacts withGLI1by pull down (View interaction)