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Negative control of cell size in the cyanobacterium Synechococcus elongatus PCC 7942 by the essential response regulator RpaB
Author(s) -
Moronta-Barrios Félix,
Espinosa Javier,
Contreras Asunción
Publication year - 2013
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2013.01.023
Subject(s) - cyanobacteria , regulator , acclimatization , microbiology and biotechnology , photosynthesis , response regulator , biology , cell , two component regulatory system , gene , regulation of gene expression , synechococcus , chemistry , biochemistry , botany , genetics , bacteria , bacterial protein , mutant
The essential NblS–RpaB pathway for photosynthesis regulation and acclimatization to a variety of environmental conditions is the most conserved two‐component system in cyanobacteria. To get insights into the RpaB implication in cell homeostasis we investigated the phenotypic impact of altering expression of the essential rpaB gene of Synechococcus elongatus PCC 7942 and determined the in vivo levels of the RpaB and RpaB∼P polypeptides. Our results implicate non‐phosphorylated RpaB in controlling cell length and shape and suggest that intrinsic regulation may be important to prevent drastic variations in RpaB levels and activity.