GalX regulates the  d ‐galactose oxido‐reductive pathway in  Aspergillus niger | Zendy

Gruben Birgit S. | Zendy; Zhou Miaomiao | Zendy; de Vries Ronald P. | Zendy

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GalX regulates the d ‐galactose oxido‐reductive pathway in Aspergillus niger

Author(s) -

Gruben Birgit S.,

Zhou Miaomiao,

de Vries Ronald P.

Publication year - 2012

Publication title -

febs letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.593

H-Index - 257

eISSN - 1873-3468

pISSN - 0014-5793

DOI - 10.1016/j.febslet.2012.09.029

Subject(s) - aspergillus niger , galactose , aspergillus nidulans , catabolism , biochemistry , chemistry , aspergillus , gene , biology , enzyme , microbiology and biotechnology , mutant

Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in d ‐galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX regulates the d ‐galactose oxido‐reductive pathway, but not the Leloir pathway in A. niger .

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