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GalX regulates the d ‐galactose oxido‐reductive pathway in Aspergillus niger
Author(s) -
Gruben Birgit S.,
Zhou Miaomiao,
de Vries Ronald P.
Publication year - 2012
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2012.09.029
Subject(s) - aspergillus niger , galactose , aspergillus nidulans , catabolism , biochemistry , chemistry , aspergillus , gene , biology , enzyme , microbiology and biotechnology , mutant
Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in d ‐galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX regulates the d ‐galactose oxido‐reductive pathway, but not the Leloir pathway in A. niger .