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Non‐enzymatic conversion of chlorophyll‐ a into chlorophyll‐ d in vitro: A model oxidation pathway for chlorophyll‐ d biosynthesis
Author(s) -
Fukusumi Takanori,
Matsuda Kohei,
Mizoguchi Tadashi,
Miyatake Tomohiro,
Ito Satoshi,
Ikeda Tsukasa,
Tamiaki Hitoshi,
Oba Toru
Publication year - 2012
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2012.05.036
Subject(s) - chlorophyll , chemistry , chlorophyll a , biosynthesis , enzyme , in vitro , biochemistry , chlorophyll c , botany , biology , chlorophyll fluorescence , organic chemistry
Chlorophyll‐ a (Chl‐ a ) was readily converted into Chl‐ d under mild conditions without any enzymes. Treatment of Chl‐ a dissolved in dry tetrahydrofuran (THF) with thiophenol and acetic acid at room temperature successfully produced Chl‐ d in 31% yield. During the acidic oxidation, removal of the central magnesium, pheophytinization, was sufficiently suppressed. This mild pathway can give insights into the yet unidentified Chl‐ d biosynthesis.

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