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Human synaptotagmin‐II is not a high affinity receptor for botulinum neurotoxin B and G: Increased therapeutic dosage and immunogenicity
Author(s) -
Strotmeier Jasmin,
Willjes Gesche,
Binz Thomas,
Rummel Andreas
Publication year - 2012
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2011.12.037
Subject(s) - synaptotagmin 1 , botulinum neurotoxin , potency , receptor , chemistry , synaptic vesicle , immunogenicity , biology , microbiology and biotechnology , pharmacology , biochemistry , antibody , vesicle , immunology , in vitro , membrane , toxin
rSyt‐II binds to BoNT/B by pull down (View Interaction: 1, 2)