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Engineered epidermal growth factor mutants with faster binding on‐rates correlate with enhanced receptor activation
Author(s) -
Lahti Jennifer L.,
Lui Bertrand H.,
Beck Stayce E.,
Lee Stephen S.,
Ly Daphne P.,
Longaker Michael T.,
Yang George P.,
Cochran Jennifer R.
Publication year - 2011
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2011.03.044
Subject(s) - epidermal growth factor receptor , epidermal growth factor , receptor tyrosine kinase , microbiology and biotechnology , receptor , mutant , tyrosine kinase , biology , signal transduction , chemistry , biochemistry , gene
humanEGFR physically interacts with humanEGF by fluorescence‐activated cell sorting (View Interaction 1, 2, 3, 4, 5, 6, 7)