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Ecdysone receptor homologs from mollusks, leeches and a polychaete worm
Author(s) -
Laguerre Michel,
Veenstra Jan A.
Publication year - 2010
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2010.10.004
Subject(s) - polychaete , biology , ecdysone , receptor , microbiology and biotechnology , chemistry , zoology , ecology , biochemistry , larva
The genomes of the mollusk Lottia gigantea , the leech Helobdella robusta and the polychaete worm Capitella teleta each have a gene encoding an ecdysone receptor homolog. Publicly available genomic and EST sequences also contain evidence for ecdysone receptors in the seahare Aplysia californica , the bobtail squid Euprymna scolopes and the medicinal leech Hirudo medicinalis . Three‐dimensional models of the ligand binding domains of these predicted ecdysone receptor homologs suggest that each of them could potentially bind an ecdysone‐related steroid. Thus, ecdysone receptors are not limited to arthropods and nematodes.