Premium
Crystal structure of the HIV‐1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site
Author(s) -
Wielens Jerome,
Headey Stephen J.,
Jeevarajah Dharshini,
Rhodes David I.,
Deadman John,
Chalmers David K.,
Scanlon Martin J.,
Parker Michael W.
Publication year - 2010
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2010.03.016
Subject(s) - allosteric regulation , integrase , chemistry , binding site , integrase inhibitor , inhibitory postsynaptic potential , human immunodeficiency virus (hiv) , binding domain , domain (mathematical analysis) , core (optical fiber) , crystal structure , stereochemistry , biochemistry , biophysics , crystallography , enzyme , virology , biology , materials science , antiretroviral therapy , dna , neuroscience , viral load , composite material , mathematical analysis , mathematics
MINT‐7713125: IN (uniprotkb:P04585) and IN (uniprotkb:P04585) bind (MI:0407) by X‐ray crystallography (MI:0114)