Crystal structure of the HIV‐1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site | Zendy

Wielens Jerome | Zendy; Headey Stephen J. | Zendy; Jeevarajah Dharshini | Zendy; Rhodes David I. | Zendy; Deadman John | Zendy; Chalmers David K. | Zendy; Scanlon Martin J. | Zendy; Parker Michael W. | Zendy

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Crystal structure of the HIV‐1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site

Author(s) -

Wielens Jerome,

Headey Stephen J.,

Jeevarajah Dharshini,

Rhodes David I.,

Deadman John,

Chalmers David K.,

Scanlon Martin J.,

Parker Michael W.

Publication year - 2010

Publication title -

febs letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.593

H-Index - 257

eISSN - 1873-3468

pISSN - 0014-5793

DOI - 10.1016/j.febslet.2010.03.016

Subject(s) - allosteric regulation , integrase , chemistry , binding site , integrase inhibitor , inhibitory postsynaptic potential , human immunodeficiency virus (hiv) , binding domain , domain (mathematical analysis) , core (optical fiber) , crystal structure , stereochemistry , biochemistry , biophysics , crystallography , enzyme , virology , biology , materials science , antiretroviral therapy , dna , neuroscience , viral load , composite material , mathematical analysis , mathematics

MINT‐7713125: IN (uniprotkb:P04585) and IN (uniprotkb:P04585) bind (MI:0407) by X‐ray crystallography (MI:0114)

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