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Vertebrate β‐thymosins: Conserved synteny reveals the relationship between those of bony fish and of land vertebrates
Author(s) -
Edwards John
Publication year - 2010
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2010.02.004
Subject(s) - synteny , vertebrate , biology , gene duplication , genome , fish <actinopterygii> , evolutionary biology , identification (biology) , gene , genetics , ecology , fishery
Using conservation of synteny I show how the four thymosins expressed by teleost fish are related to the three of tetrapods, which is not evident from their protein sequences. This clarification was aided by identification of a novel thymosin of reptilians that replaces the β10 thymosin of mammals. Recent reconstruction of the ancestral vertebrate genome suggests that divergence of β‐thymosins began with duplication preceding the two rounds of whole genome duplication.