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Genomic analysis of a novel integrative conjugative element in Vibrio cholerae
Author(s) -
Taviani Elisa,
Grim Christopher J.,
Chun Jongsik,
Huq Anwar,
Colwell R.R.
Publication year - 2009
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2009.10.041
Subject(s) - vibrio cholerae , mobile genetic elements , horizontal gene transfer , genome , biology , bacteria , microbiology and biotechnology , gene , genetics
Integrative conjugative elements (ICEs) are a class of self‐transmissible mobile elements that mediate horizontal gene transfer in bacteria, and play an important role in bacterial evolution. Since 1992, ICEs of the SXT/R391 family have been found to be widely distributed among Vibrio cholerae strains isolated in Asian countries. Here we describe ICE Vch B33, an ICE found in the genomes of two V. cholerae O1 Eltor strains, one isolated in India, 1994, and the other from Mozambique, 2004. ICE Vch B33 revealed a new genetic organization, different from other ICEs of the SXT/R391 family, demonstrating the genomic plasticity of these elements.