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Membrane glycolipids in stem cells
Author(s) -
Yu Robert K.,
Suzuki Yusuke,
Yanagisawa Makoto
Publication year - 2010
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2009.08.026
Subject(s) - stem cell , microbiology and biotechnology , embryonic stem cell , adult stem cell , caveolae , biology , glycolipid , lipid raft , mesenchymal stem cell , cellular differentiation , chemistry , immunology , biochemistry , signal transduction , gene
Stem cells, such as embryonic stem cells, hematopoietic stem cells, neural stem cells, mesenchymal stem cells, and very small embryonic‐like stem cells, are undifferentiated cells that are endowed with a high potential for proliferation and the capacity for self‐renewal with retention of pluri/multipotency to differentiate into their progenies. Recently, studies regarding the biological functions of glycolipids and cell surface microdomains (caveolae, lipid rafts, or glycolipid‐enriched microdomains) in stem cells are emerging. In this review, we introduce the expression patterns of glycolipids and the functional roles of cell surface microdomains in stem cells.