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Ribavirin enhances interferon signaling via stimulation of mTOR and p53 activities
Author(s) -
Su Wen-Cheng,
Liu Wei-Liang,
Cheng Ching-Wei,
Chou Yu-Bin,
Hung Ko-Hsuan,
Huang Wen-Hung,
Wu Chao-Liang,
Li Yuan-Tsung,
Shiau Ai-Li,
Lai Ming-Yang
Publication year - 2009
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2009.07.027
Subject(s) - ribavirin , pi3k/akt/mtor pathway , interferon , signal transduction , cancer research , biology , microbiology and biotechnology , chemistry , pharmacology , immunology , virus , hepatitis c virus
mTOR (uniprotkb:P42345) physically interacts (MI:0914) with P53 (uniprotkb:P04637) by anti bait coimmunoprecipitation (MI:0006)