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HSP90 is required for TAK1 stability but not for its activation in the pro‐inflammatory signaling pathway
Author(s) -
Liu Xin Yu,
Seh Cheah Chen,
Cheung Peter C.F.
Publication year - 2008
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2008.10.053
Subject(s) - hsp90 , heat shock protein , microbiology and biotechnology , cdc37 , signal transduction , chemistry , regulator , kinase , tumor necrosis factor alpha , protein kinase a , map kinase kinase kinase , cancer research , biochemistry , biology , immunology , gene
MINT‐6797182:TAK1 (uniprotkb:O43318‐2) physically interacts (MI:0218) with CDC37 (uniprotkb:Q16543) and HSP90 (uniprotkb:P07900) by anti bait coimmunoprecipitation (MI:0006) MINT‐6797194:TAK1 (uniprotkb:O43318‐2) physically interacts (MI:0218) with TAB1 (uniprotkb:Q15750), HSP90 (uniprotkb:P07900) and CDC37 (uniprotkb:Q16543) by anti bait coimmunoprecipitation (MI:0006) MINT‐6797248:TAK1 (uniprotkb:Q62073) physically interacts (MI:0218) with HSP90 (uniprotkb:P07901), CDC37 (uniprotkb:Q61081), TAB2 (uniprotkb:Q99K90) and TAB1 (uniprotkb:Q8CF89) by anti bait coimmunoprecipitation (MI:0006) MINT‐6797232:TAK1 (uniprotkb:O43318‐2) physically interacts (MI:0218) with HSP90 (uniprotkb:P07900) and CDC37 (uniprotkb:Q16543) by pull down (MI:0096) MINT‐6797216:TAK1 (uniprotkb:O43318‐2) physically interacts (MI:0218) with TAB2 (uniprotkb:Q9NYJ8), CDC37 (uniprotkb:Q16543), HSP90 (uniprotkb:P07900) and TAB1 (uniprotkb:Q15750) by anti bait coimmunoprecipitation (MI:0006)