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Pectenotoxin‐2 represses telomerase activity in human leukemia cells through suppression of hTERT gene expression and Akt‐dependent hTERT phosphorylation
Author(s) -
Kim Mun-Ock,
Moon Dong-Oh,
Kang Sang-Hyuck,
Heo Moon-Soo,
Choi Yung Hyun,
Jung Jee Hyung,
Lee Jae-Dong,
Kim Gi-Young
Publication year - 2008
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2008.08.030
Subject(s) - telomerase reverse transcriptase , telomerase , phosphorylation , telomere , cancer research , protein kinase b , gene , leukemia , chemistry , gene expression , biology , microbiology and biotechnology , genetics
MINT‐ 6742762 : hTERT (uniprotkb: O14746 ) physically interacts (MI: 0218 ) with AKT (uniprotkb: P31749 ) by anti bait coimmunoprecipitation (MI: 0006 )