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Only plant‐type (GLYK) glycerate kinases produce d ‐glycerate 3‐phosphate
Author(s) -
Bartsch Oliver,
Hagemann Martin,
Bauwe Hermann
Publication year - 2008
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2008.07.038
Subject(s) - phosphate , biochemistry , kinase , strain (injury) , biology , nostoc , bacteria , cyanobacteria , genetics , anatomy
d ‐Glycerate kinases (GK) occur in three phylogenetically distinct classes. Class II GKs produce glycerate 2‐phosphate, while both class I GK and class III GK (GLYK) are thought to produce glycerate 3‐phosphate. We report on the identification of a bacterial‐type class I GK in the unicellular cyanobacterium Synechocystis sp. strain PCC 6803 and of a plant‐type GLYK in the filamentous cyanobacterium Nostoc sp. strain PCC 7120. The comparison with other prokaryotic and eukaryotic GKs of both classes shows that glycerate 3‐phosphate is produced only by the GLYKs, but, in contrast to current thinking, not by any of the examined class I enzymes.