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Ribonuclease activity is a common property of Arabidopsis CCCH‐containing zinc‐finger proteins
Author(s) -
Addepalli Balasubrahmanyam,
Hunt Arthur G.
Publication year - 2008
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2008.06.029
Subject(s) - zinc finger , arabidopsis , ribonuclease , nuclease , zinc finger nuclease , biology , genetics , chemistry , rna , gene , transcription factor , mutant
The CCCH class of zinc fingers occurs in a large number of Arabidopsis proteins. Previous studies revealed that one such protein is a nuclease, the activity of which is attributable to one of the CCCH motifs. To examine whether nuclease activity is a more general characteristic of CCCH zinc finger containing proteins, five other such Arabidopsis proteins were assayed for a similar activity. The results indicate that all of these proteins possess nuclease activity. Thus, nuclease activity may be a common characteristic of Arabidopsis CCCH‐containing proteins.