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Arabidopsis thaliana inositol 1,3,4‐trisphosphate 5/6‐kinase 4 (AtITPK4) is an outlier to a family of ATP‐grasp fold proteins from Arabidopsis
Author(s) -
Sweetman Dylan,
Stavridou Ioanna,
Johnson Sue,
Green Porntip,
Caddick Samuel E.K.,
Brearley Charles A.
Publication year - 2007
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2007.07.046
Subject(s) - inositol , arabidopsis , biology , kinase , biochemistry , arabidopsis thaliana , enzyme , genetics , gene , receptor , mutant
The Arabidopsis genome encodes a family of inositol 1,3,4‐trisphosphate 5/6‐kinases which form a subgroup of a larger group of ATP‐grasp fold proteins. An analysis of the inositol 1,3,4‐trisphosphate 5/6‐kinase family might, ultimately, be best rewarded by detailed comparison of related enzymes in a single genome. The enzyme encoded by At2G43980, AtITPK4; is an outlier to its family. At2G43980 is expressed in male and female organs of young and mature flowers. AtITPK4 differs from other family members in that it does not display inositol 3,4,5,6‐tetrakisphosphate 1‐kinase activity; rather, it displays inositol 1,4,5,6‐tetrakisphosphate and inositol 1,3,4,5‐tetrakisphosphate isomerase activity.