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Characterization of Arabidopsis decapping proteins AtDCP1 and AtDCP2, which are essential for post‐embryonic development
Author(s) -
Iwasaki Shintaro,
Takeda Atsushi,
Motose Hiroyasu,
Watanabe Yuichiro
Publication year - 2007
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2007.04.051
Subject(s) - arabidopsis , embryogenesis , embryonic stem cell , microbiology and biotechnology , arabidopsis thaliana , biology , characterization (materials science) , chemistry , biochemistry , embryo , gene , nanotechnology , mutant , materials science
Although decapping is an important process in eukaryotic mRNA turnover, little is known about this process in plants. Here, we identified Arabidopsis thaliana decapping proteins AtDCP1 and AtDCP2 and showed that (I) AtDCP2 is an active decapping enzyme, (II) AtDCP1 interacts with itself, (III) AtDCP1 and AtDCP2 are localized to cytoplasmic foci (putative Arabidopsis processing body), and (IV) AtDCP1 and AtDCP2 are essential for post‐embryonic development. Our findings provide new insights into the role of decapping‐dependent mRNA turnover.