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Glucose repression over Saccharomyces cerevisiae glycerol/H + symporter gene STL1 is overcome by high temperature
Author(s) -
Ferreira Célia,
Lucas Cândida
Publication year - 2007
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2007.03.086
Subject(s) - glycerol , psychological repression , symporter , saccharomyces cerevisiae , chemistry , biochemistry , yeast , gene expression , gene , transporter
High temperature promotes an improved activity of the Saccharomyces cerevisiae glycerol/H + symporter encoded by STL1 , which correlates well with Stl1p levels. This happens in both fermentable and respiratory metabolic growth conditions, though the induction in the latter is much higher. The relief of glucose repression by high temperature at the level of protein expression and activity (Stl1p) is reported for the first time. We reason that the glycerol internal levels fine‐tuning, under heat‐stress as in other physiological condition, can be achieved with the contribution of the tight regulation of the symporter.