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What can Caenorhabditis elegans tell us about the nuclear envelope?
Author(s) -
Gorjánácz Mátyás,
Jaedicke Andreas,
Mattaj Iain W.
Publication year - 2007
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2007.03.052
Subject(s) - caenorhabditis elegans , envelope (radar) , biology , genetics , computer science , gene , telecommunications , radar
The nuclear envelope (NE) of the eukaryotic cell provides an essential barrier that separates the nuclear compartment from the cytoplasm. In addition, the NE is involved in essential functions such as nuclear stability, regulation of gene expression, centrosome separation and nuclear migration and positioning. In metazoa the NE breaks down and re‐assembles around the segregated chromatids during each cell division. In this review we discuss the molecular constituents of the Caenorhabditis elegans NE and describe their role in post‐mitotic NE re‐formation, as well as the usefulness of C. elegans as an in vivo system for analyzing NE dynamics.