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Ribosomal protein S1 induces a conformational change of the 30S ribosomal subunit
Author(s) -
Agalarov Sultan Ch.,
Kalinichenko Artem A.,
Kommer Aigar A.,
Spirin Alexander S.
Publication year - 2006
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2006.11.036
Subject(s) - 30s , ribosomal protein , ribosomal rna , eukaryotic large ribosomal subunit , protein subunit , eukaryotic small ribosomal subunit , conformational change , chemistry , ribosome , 50s , eukaryotic ribosome , biophysics , biochemistry , biology , 18s ribosomal rna , rna , gene
A comparative study of the 30S ribosomal subunit in the complex with protein S1 and the subunit depleted of this protein has been carried out by the hot tritium bombardment method. Differences in exposure of some ribosomal proteins within the 30S subunit depleted of S1 and within the 30S–S1 complex were found. It was concluded that protein S1 binds in the region of the neck of the 30S ribosomal subunit inducing a conformational change of its structure.