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PolydA and polyrA self‐structured by a europium and amino acid complex
Author(s) -
Zhang Haiyuan,
Yu Haijia,
Ren Jinsong,
Qu Xiaogang
Publication year - 2006
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2006.05.046
Subject(s) - europium , chemistry , valine , dna , amino acid , aspartic acid , rna , duplex (building) , salt (chemistry) , stereochemistry , biochemistry , organic chemistry , gene , ion
Different DNA selectivity was found for the newly synthesized europium– l ‐valine complex. Unexpected DNA and RNA selection results showed that europium– l ‐valine complex can cause single‐stranded polydA and polyrA to self‐structure. The sigmoidal melting curve profiles indicate the transition is cooperative, similar to the cooperative melting of a duplex DNA. This is different from another europium amino acid complex, europium– l ‐aspartic acid complex which can induce B‐Z transition under the low salt condition. To our knowledge, there is no report to show that a metal–amino acid complex can cause the self‐structuring of single‐stranded DNA and RNA.