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MRI‐guided gene therapy
Author(s) -
Yang Xiaoming,
Atalar Ergin
Publication year - 2006
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2006.04.027
Subject(s) - genetic enhancement , transfection , gene , gene delivery , gene expression , transduction (biophysics) , function (biology) , magnetic resonance imaging , computational biology , medicine , biology , bioinformatics , pathology , radiology , microbiology and biotechnology , genetics , biophysics
MRI has the ability to generate high‐contrast and high‐resolution images, to obtain multiple diagnostic evaluations of organ function and morphology, and to provide multiple image planes with no risk of ionizing radiation. Recent efforts have focused on using MR technology to monitor gene delivery, to enhance gene transfection/transduction, and to track gene expression. This review summarizes the current status of MRI‐guided gene therapy.