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Hansenula polymorpha and Saccharomyces cerevisiae Pex5p's recognize different, independent peroxisomal targeting signals in alcohol oxidase
Author(s) -
Ozimek Paulina,
Kötter Peter,
Veenhuis Marten,
van der Klei Ida J.
Publication year - 2006
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2005.11.045
Subject(s) - saccharomyces cerevisiae , peroxisome , chemistry , alcohol oxidase , biochemistry , oxidase test , alcohol , yeast , enzyme , gene , recombinant dna , pichia pastoris
In contrast, HpPex5p‐mediated sorting of AO into S. cerevisiae peroxisomes is independent of the PTS1, but requires an alternative PTS that is only formed when HpPyc1p is co‐produced and most likely involves folding and co‐factor binding to AO.