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Consistency of genome‐based methods in measuring Metazoan evolution
Author(s) -
Zdobnov Evgeny M.,
von Mering Christian,
Letunic Ivica,
Bork Peer
Publication year - 2005
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2005.04.006
Subject(s) - genome , biology , caenorhabditis , caenorhabditis elegans , divergence (linguistics) , evolutionary biology , genetics , molecular clock , genetic algorithm , phylogenetics , gene , linguistics , philosophy
Seven distinct genome‐wide divergence measures were applied pairwise to the nine sequenced animal genomes of human, mouse, rat, chicken, pufferfish, fruit fly, mosquito, and two nematode worms ( Caenorhabditis briggsae and Caenorhabditis elegans ). Qualitatively, all of these divergence measures are found to correlate with the estimated time since speciation; however, marked deviations are observed in a few lineages. The distinct genome divergence measures also correlate well among themselves, indicating that most of the processes shaping genomes are dominated by neutral events. The deviations from the clock‐like scenario in some lineages are observed consistently by several measures, implicitly confirming their reliability.