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Fractal nature of chromatin organization in interphase chicken erythrocyte nuclei: DNA structure exhibits biphasic fractal properties
Author(s) -
Lebedev D.V.,
Filatov M.V.,
Kuklin A.I.,
Islamov A.Kh.,
Kentzinger E.,
Pantina R.,
Toperverg B.P.,
Isaev-Ivanov V.V.
Publication year - 2005
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2005.01.052
Subject(s) - chromatin , fractal , fractal dimension , nucleus , interphase , scattering , chemistry , dna , crystallography , biophysics , physics , biology , optics , biochemistry , mathematics , genetics , microbiology and biotechnology , mathematical analysis
Arrangement of chromatin in intact chicken erythrocyte nuclei was investigated by small angle neutron scattering. The scattering spectra have revealed that on the scales between 15 nm and 1.5 μm the interior of the nucleus exhibited properties of a mass fractal. The fractal dimension of the protein component of cell nucleus held constant at approximately 2.5, while the DNA organization was biphasic, with the fractal dimension slightly higher than 2 on the scales smaller than 300 nm and approaching 3 on the larger scales.