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Telomeres and telomerase: their mechanisms of action and the effects of altering their functions
Author(s) -
Blackburn Elizabeth H.
Publication year - 2005
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/j.febslet.2004.11.036
Subject(s) - telomerase , telomere , telomerase rna component , chromosome , eukaryotic chromosome fine structure , function (biology) , microbiology and biotechnology , biology , dna , genetics , chemistry , telomerase reverse transcriptase , gene
The molecular features of telomeres and telomerase are conserved among most eukaryotes. How telomerase and telomeres function and how they interact to promote the chromosome‐stabilizing properties of telomeres are discussed here.