Open Access
Efficiency of diffusion weighted magnetic resonance in differentiation between benign and malignant endometrial lesions
Author(s) -
Ahmed Elsammak,
S. A. Shehata,
Mona Abulezz,
Ghada K. Gouhar
Publication year - 2017
Publication title -
the egyptian journal of radiology and nuclear medicine /the egyptian journal of radiology and nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 13
eISSN - 2090-4762
pISSN - 0378-603X
DOI - 10.1016/j.ejrnm.2017.02.008
Subject(s) - medicine , magnetic resonance imaging , radiology , vaginal bleeding , diffusion mri , endometrium , ultrasound , effective diffusion coefficient , nuclear medicine , pregnancy , biology , genetics
Objectives: To assess the role of DW-MRI and ADC values in distinguishing benign from malignant endometrial disorders. Patients and methods: Pelvic ultrasound, conventional MRI, DW-MRI and histopathologic examinations were done for 42 female patients with abnormal vaginal bleeding. Mean ADC values of endometrial lesions were calculated and compared. Results: Endometrial malignancies showed significant low ADC values (0.82Â +Â 1.09Â ÃÂ 10â3Â mm2/s) compared to benign lesions (1.44Â +Â 0.15Â ÃÂ 10â3Â mm2/s) (p: 0.000). Using 1.19Â ÃÂ 10â3Â mm2/s as cut-off value for distinguishing malignant from benign lesions achieved 88.9% sensitivity and 100% specificity. Conclusion: DW-MRI is useful in distinguishing malignant from benign endometrial lesions and tumor staging as well. Keywords: Pelvic DWI-MRI, Endometrial lesions, ADC valu