Open AccessReliability of magnetic susceptibility weighted imaging in detection of cerebral microbleeds in stroke patients
Author(s) -
Lamiaa El-Serougy,
Mohamed M. Elrakhawy,
Germeen Albair Ashamallah,
Wessam Mustafa
Publication year - 2017
Publication title -
the egyptian journal of radiology and nuclear medicine /the egyptian journal of radiology and nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 13
eISSN - 2090-4762
pISSN - 0378-603X
DOI - 10.1016/j.ejrnm.2016.11.003
Subject(s) - susceptibility weighted imaging , medicine , stroke (engine) , kappa , acute stroke , magnetic resonance imaging , cohen's kappa , radiology , nuclear medicine , mechanical engineering , linguistics , philosophy , machine learning , tissue plasminogen activator , computer science , engineering
ObjectiveWe investigated the reliability of susceptibility weighted imaging (SWI) in detecting cerebral microbleeds in stroke patients which predicts future recurrence and judges thrombolytic drugs.MethodsA total of 124 patients referred from stroke unit underwent conventional MRI and SWI. Two observers reviewed twice the SWI separately to identify presence, anatomical location and count of cerebral microbleeds. Inter and intraobserver agreement were calculated using Kappa statistics.ResultsIn SWI, intraobserver agreement for presence of CMBs in any brain location was almost perfect for both observers (K=0.86, p<0.01, 95% CI=0.83–0.89) (K=0.94, p<0.01, 95% CI=0.92–0.96), the interobserver agreement was almost perfect for first and second times (k=0.95, p<0.01, 95% CI=0.94–0.96), (k=0.84, p<0.01, 95% CI=0.8–0.89). Intraobserver agreement was almost perfect for the identified CMBs in each of the three main brain locations : lobar (k=0.9, p<0.01 95% CI=0.8–1), deep (k=0.81 p<0.01, 95% CI=0.71–0.91) and infratentorial (k=0.95 p<0.01, 95% CI=0.9–1).ConclusionSWI is an important reliable technique allows accurate detection of CMBs occurring in association with hemorrhage in acute and chronic stroke and should be included in the protocols for assessment of stroke to help in choice of proper treatment and prediction of future attacks