Open AccessRole of 3-T diffusion-weighted magnetic resonance imaging in differentiation between benign and malignant hepatic lesions
Author(s) -
Mohamed T. Ali,
Mohammad Osman,
Mohamed D. Homos,
Doaa Mohamed Nabil
Publication year - 2016
Publication title -
the egyptian journal of radiology and nuclear medicine /the egyptian journal of radiology and nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 13
eISSN - 2090-4762
pISSN - 0378-603X
DOI - 10.1016/j.ejrnm.2016.08.007
Subject(s) - medicine , diffusion mri , magnetic resonance imaging , effective diffusion coefficient , cutoff , pathology , radiology , nuclear medicine , physics , quantum mechanics
Aim: To evaluate the ability of DWIs to distinguish between benign and malignant focal hepatic lesions (FHLs) using 3 T MR.Material and methods: A total of 73 FHLs in 48 patients were evaluated. There were 28 benign lesions including 13 hemangiomas (17.8%), 8 hepatic cysts (10.9%), 4 regenerating hepatic nodules (5.4%), 2 adenomas (2.7%) and 1 focal fatty infiltration (1.3%). The others 45 lesions were malignant including 28 hepatocellular carcinomas (38.3%), 15 metastases (20.5%) and 2 cholangiocarcinomas (2.7%). The study used two b values (0 and 800 s/mm2) and the ADC values were calculated.Results: The mean ADC value for simple liver cysts was 2.58 ± 0.35 × 10−3 mm2/s, for solid benign lesions was 1.63 ± 0.41 × 10−3 mm2/s and for malignant lesions was 1.21 ± 0.38 × 10−3 mm2/s with statistical difference (p < 0.0001). We found that the best ADC cutoff value was 1.49 × 10−3 mm2/s with accuracy of 83.6% in differentiation between the all benign and malignant FHLs. While with exclusion of the cystic hepatic lesions, the best ADC cutoff value was reduced to be 1.35 × 10−3 mm2/s with accuracy of 78.5%.Conclusions: DWI can be used to differentiate between the benign and malignant FHLs